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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c14809dae7e4b068269c3e339b4acd1adb07ec56d4ae2b2e852a03f4e3c827f' 
  AND token = 'g0dNJcLsxbB2T4/nuEb/JICqZz7ThdkJXdiGovKYdbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}