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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50f4168e21c7ed97396b03389d7ee054ca8ed330ecfd43ff0912ac88e80d3e1' 
  AND token = 'aEU+LNrDTz8uvv9pKQQucIhGPMlAqMcPXw64FDfT4RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}