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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dab5b6d526044791a9dc84f1c84cd5124e24eded8bec291b26c92486e646534' 
  AND token = 'vGDob73VT5WViBx+0PSiWv9RBqF4A0vwfkOhr3PdDDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}