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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b67eb4bafd4ed4068c29533b60d3d6aac8359fa101c7c6e787290a39377048' 
  AND token = 'Eu7IDZiY7LPwufVcV7J960UoBElQogNZWZvq6Z6UbCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}