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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9b74fddaa40be2dc21e3919b89b12eb904ef279ba3d20439c7e6edf3b6514d2' 
  AND token = 'pgQWgg4by132I7El6XkGP7//ytQk2h7Bnwk1WE5MVdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}