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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7336c1ce486df3903cc09c1a3fed5221b126b94b2c74491c9965869d7e47c4' 
  AND token = '2eai7YX6UvKLrfRzCoZhEudlIunSN7KW1+7YV9ndr98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}