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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994b7e243eb29f44bddc016195e900a7d1681a3370fd00c4c5eb88e6297e79da' 
  AND token = 'lbqutY/GbSd5+thNF+UY9kuFi2WIG1iFJaiI/YerC8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}