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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef78743c8206a49d5967633ade513c6d240036d3605eda98580f9b2547ae94d3' 
  AND token = '2J0SgiMQLHffR0vmo9uCU7V6rpxqXNt04jqO2Z0+FB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}