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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6142c224d96a315fdc7ba0685b10cdd193e24741be9ffc743a3747761426e402' 
  AND token = 'R10vCwV+RJjp7xDtU146bdtLYHaKoz/Rr4RpgfYtai8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}