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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8be2163ed36dba597495b4cd73225043b4ee5208a9e6db53a3e183f05681ddf9' 
  AND token = 'pn+A/mOaFuoQgpX5S1oo1qU6MFGUoZYAFAgteD2mH3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}