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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54230ec673b083dc658bc503e0acf58111c3e0ba7f129b15eee456404f1a4083' 
  AND token = 'qJ7xNo1tx3Ij4nmsLnbcYdlxSihnhWG1OiC22NwTi0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}