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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2d343b2b2fded56d95cb8295a2023737963fab34a738456a013d9b4121fad9' 
  AND token = '8tRxy6crnez4CeAyrUXoay6w1b1SAEyglctbVX+v3MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}