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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1045f73dbaf034c2a17a2337a752a1a643d8d1548039a78445162c363c14b306' 
  AND token = 'yp+eiMwMy/mVvYLciIguDPe+kd4qYLQANagmYwCKqGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}