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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc9bf7a57096e7925561ce85710a029a58922a2cd3fda361a8527df8f5bd8b8' 
  AND token = 'V3E7OXwPOemmlVMos4tj1X8/DWMbVVJy2OWz4fR2ZSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}