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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c22ee73d52f0ece08623af787eb97b772b1a12b8eddb5d21eedc820f506199' 
  AND token = 'RDIlwrMNYkU42JZEifc2GClzjQlgEha1BIjA92CL9Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}