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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0ac345d6b60b598ed2af2dd3c7840ef7d2f8ac1a322c35419fcb82deb4e505' 
  AND token = 'EYiGfL9bV2+65R356eIqFdsdxkDOgJWZlZmHYF1wIjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}