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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21fdd32b59635f79ab10b2d5b6211b456ad2899dcbfee2f0b6b6227b2ab1509' 
  AND token = 'DB/qKLZUu33AZBtx4+bbzpdwgz6L1E5clVwUVAr1y3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}