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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943166cf7aa0fe35a60e26182f6849b70b83b38220527018855fe3e51bc58b58' 
  AND token = 'lhE+pqQfLax0KNNnb52sdsyMRq+bKY2s+SLwjJaa/6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}