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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6b6ad8d0e9454bb7ac78e990a8180761090950c67b70155b5dd40701c2c740' 
  AND token = 'IuW2qVMKKd6RKJg4IS5MP85aDQlPFIOPR5sb2A50mdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}