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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95729e9736c680fe1f4dc4b49ac2f2fecbdbb892053c7f598ab7863627608001' 
  AND token = '/dJchNUZrSuHzC2lQpW9IC0IBnP3zxdrmrk31gCHjiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}