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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da1ffc6b99dac3a9d807e1e4224008a1839d5bd6d790b9927beb697508884c2c' 
  AND token = 'IQsG2dEIPrP6wEQ4TH2S/6S0JIsYBE328nJn2uwpGTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}