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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0341bc860027b643aa15372c610b00e19870eb1815cf643cb22d3566261bb4f8' 
  AND token = 'uAIFRWIxvJliCr8tkN+SVutJ+p2SIx6mMKF7usS0TA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}