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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd0ebbbfb1045072f7c163de9302784e71de5a21fe1c1c1d1c3f0e20218fe483' 
  AND token = '2+16E/pp5kAep4i147WXp5gblXQYzRQ5UomjUfhxz2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}