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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb8c6fe75bc35270f8d467d0f246fd2f650fa145a277b9d939237464d8b90d1' 
  AND token = 'EtaSQb7rh6uoJuQjYb2Iz2kpJvut1XRfvIvNIGb/SPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}