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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac6a0125a7f7f150005503797e4a9d354e6f86ce00e6b5b2629289df09f8669' 
  AND token = 'c7nVAsdTEk0FIUvjEHXZiqyCxHswAjqQhaym6MWMWNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}