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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b50b60bac10e9885951b2f1d5a9de053ccaa9fff90f6a420c554fa45a80f608' 
  AND token = 'TkumB3x5oyI+kgQZ3qDfIPnNxE4Xu5lZWBCQXMI9Uq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}