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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464f5d90690a7aed281092ec9254a5f8d59d6bee7ad0dd695b686c7f545bde8f' 
  AND token = 'yl0vzQ0bTpimSpkHleYcfu8JOY2Y+lntQd/kbYlwwAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}