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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd19a2220d9b1bdbdc21e1a67cf101c4a20d8a4343d35c969d03899d8cc1036' 
  AND token = 'x7+4Hpvx5/1Qyz6eDjbshGremD60+C7ahZISGQB4Fy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}