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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d2f91141862af9beecd22a1c3754c27ebdc6b7b3968df79cb07d507418ac60' 
  AND token = 'gK3Ya0etPCONEhN3xnhazNKkfcVzwuiw5uCso6SDBcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}