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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4553bd6512c1ab0bf4984b845e4f3514ce86c1af047b8966a063a6f4c6de16d2' 
  AND token = 'VZsAJyoS4TcQoPPgU8IzQbR6ZYXzi8boy33ZROMn+SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}