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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf075cae4b92e6ec9fba0f6e69c81911916fd06c30a6017d638f0bb3288e67de' 
  AND token = 'vix9601X0W1+YTcbBdOxJq+fMQZFl4NunGnBwQOXBfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}