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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550d577bb20fe4847eb3a22aa94a79aef290ef22e4e7188044b282e1edfb3b54' 
  AND token = '8xmZOjFwDTo06M0Cj+WxNBoSMUmxumGunsZcAK4H8KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}