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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e517e8906d036999f7e43b26af89acd9925881963466858b4552671b253ca1ac' 
  AND token = 'JTWNF0Ag6+DeYSS461bUv4mWlHNN5/yBev0tQsl6YQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}