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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a8c831dc03de5b7811800f02b65ada7bc4eca04a0323147a6f46e008f6adde' 
  AND token = 'xKPdWpwPUKYVeunYgxTP+e1MR9GGjy+JspwcXXVsHnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}