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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2b3f6d72f87dbef17700165d9119c83630b82eb6d46aa9d2bd2aa69548d3ef' 
  AND token = 'KKvOF/K0MBpqnC8NRnMMnA6gkb9iynw5n2Pbx11v67c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}