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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a04f25f531c5c0297f20c8c4bfa35494623d2a2e83e13fc133598ee2e03fb6' 
  AND token = 'PFyarK5/NBsYsM5JeqDC/j6Jtc4rJ/WY2YywYwiV1b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}