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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795ef8584520670a15f69de76cf19df05745287fb12e1e5f5e510ceb6521b03b' 
  AND token = 'DoTGnmHj+HV9xMNyZqnUrzNoiqW2u0z1v4s31jjqeqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}