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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1bd4e5d911a4def75b04bfb02f0cad86c7652b366b42856807d7848daaddcd' 
  AND token = 'SXtqlHv8eFHrNRM0leVBVuR3vdxjeetJcjJXjN/aHTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}