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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46703ccd40724c0beafadf25bdc8fbb2a185e47e0affc01b3d8649635198676' 
  AND token = 'gRQAO1KnQeCvtM38mI6e7PBx8B93smOeGNIWM4HIBCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}