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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7cfe5e5fc77aa13feebe2eea5fbe7673755273999a512f5102a1d5da4a004f' 
  AND token = '74jquYLJV+RrMptee3AjuypNEJLMLXfOE0ikPphTmss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}