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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc7e18d713873e1f775f7f05afcb8917e52657ba2e5e7ccd3bc5800b9e2e960' 
  AND token = '+Y4QQ8vTj/KpAqLtsl9fqpzqFmPWqoNTnwbSr5BjQO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}