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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e156ccb84e7c1f701d64c0c9630f06feb1c4f0abcc4e74e4fc20dbd17148d746' 
  AND token = 'qkqR/5dwR+aC6IZ7WGFg7loWjKadhuIFILAysNKzxVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}