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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7381683d2f04790af2f2634d50863825df3ba157012875e10aca0e548dfa16a' 
  AND token = 'upWYfNFTjbGSerhvs7H0IITO8/CVSyb2huvXY0s6Etc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}