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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7bfd7c34a6a73c100ea9d7b70ca314f5a874778a21f58443a7715402635674' 
  AND token = 'oOoe6QuscoP1DWvinSLlGtMNMfYpQ2Ls3UaBWVXcmgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}