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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '947f22a16faae0172041716569c5f1af219fcdddc95a6c24e2d36053d1850180' 
  AND token = 'FYOFff/SV4n8/U2LocDvrT3vS0NIzJkOWt7kE1V/jSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}