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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b62ea00d8a648f63890a308375c1e1120d037cb18676a36ad62256ee38ac1aa' 
  AND token = 'PResGWAXveHTzgjL4w02Z6+y762SxxkLExl/7wUmVLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}