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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b4d65420b07180630218992b88ada3d0c95af91cfa74e501ca25ecd6e0729d' 
  AND token = 'lht/HfGy1r+AGrL0HzitGY2F+mVqKWbG7hH6E/cMRt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}