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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f848e9da34c43b5dfbf71781fb6c75e079119f3018da3eccb8134369594ed9' 
  AND token = 'rNCLXDey+PgTFLd8oYrYwOqHfTFapb+V9TojiGXqips=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}