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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff08d338db655efac8e8eca374f2f2aeac167e7f5c59ee18c29788a297dc8e03' 
  AND token = 'o6GLA4OOii4IpdqrT8RH1QbEQtn32V0TQaJAM3CrpYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}