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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b0cfb38d96647a1a81be80f483153fa8b20d80c591a229521fa129f1b8c12a' 
  AND token = '57cJIrJ8oruT07u4rgpuj/Q49YVgW72v4744zKatles=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}